Dennis R. Burton & Eric J. Topol –

The rapid development and delivery of highly effective COVID-19 vaccines less than a year after the emergence of the disease is a huge success story. This was possible, in part, because of certain properties of the coronavirus SARS-CoV-2 that favour vaccine design — in particular, the spike protein on the virus’s surface. This prompts the body to make protective neutralizing antibodies (proteins that bind to viruses and prevent them from infecting human cells). These are most likely to be responsible for the efficacy of current COVID-19 vaccines.

Read the full article in Nature.